This publication contains information on congenital anomalies detected in babies delivered in England between 1 January and 31 December 2021. This is the seventh annual congenital anomaly statistics report released by the National Congenital Anomaly and Rare Disease Registration Service (NCARDRS) and the fourth report to contain national data for England.

For the first time, we report on the relationship between congenital anomaly total birth prevalence (per 10,000 total births) and deprivation, as measured by the Index of Multiple Deprivation (IMD) at the postcode of residence at delivery

Spreadsheet data tables with detailed estimates and a technical details document are attached to this report; these can be found on the accompanying CD-ROM.