Drugs and the Liver

Drugs and the Liver is designed to assist practitioners in making pragmatic choices for their patients.

Liver disease is a widespread and increasing problem throughout the world, however little is published on how different types and degrees of liver dysfunction affect the body's ability to handle medicines.

This book aims:

• to enable the practitioner to assess liver function using biochemical markers, other tests, signs, symptoms and disease knowledge
• to identify which pharmacokinetic and pharmacodynamic parameters of a drug are likely to be affected by different types of liver disease
• to consider the impact of a drug's side effects on a patient with liver disease.

This practical guide covers background information on liver function, the principles of drug use in liver disease and includes a section of worked examples of commonly asked questions. It will be invaluable to clinical pharmacists and anyone making medicine choices in patients with liver impairment.