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Pharmaceutical Toxicology

Pharmaceutical Toxicology
Pharmaceutical Toxicology
Safety sciences of drugs


£35.62
RRP: £37.50 You save £1.88 (5.0%)





ISBN: 9780853695936
Publisher: Pharmaceutical Press
Date Published: Jun 2006
Format: Paperback

This is the first title in the ULLA Pharmacy Series: an innovative line of introductory textbooks on pharmaceutical science for students produced by the ULLA Consortium (European Consortium for Advanced Pharmaceutical Education and Research)

Toxicology studies are carried out on all drug substances to ensure safety. This book provides an overview of the methodology and requirements of pre-clinical safety assessments of new medicines. With the focus on medicinal drugs - the most important safety issues of drugs are covered, including registration requirements of new drugs and pharmacovigilance.

After a general introduction and a number of chapters on basic toxicological principles, organ toxicity of drugs is illustrated by chapters on toxicity in the liver, in the kidney, in the respiratory system and in the immune system.

This is an introductory text for students at BSc, MSc and PhD levels,and will be an excellent companion to pharmacology textbooks, combining a broad treatment of the issues relevant for assessing the safety/efficacy balance of a new drug with information on the toxicological knowledge base and methodology.

Contents:
1. General Toxicology
2. Drug Metabolism: Inactivation and Bioactivation of Xenobioptics
3. Molecular and Cellular Mechanisms of Toxicity
4. Teratology
5. Genotoxicity
6. Carcinogenicity of Drugs
7. Liver Toxicity
8. Kidney Toxicity
9. Toxicology in the Respiratory System
10. Immunotoxicity
11. Clinical Toxicology
12. Safety Assessment of Pharmaceuticals: Regulatory Aspects
13. Pharmacovigilance


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