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Drugs and the Liver

Drugs and the Liver
Drugs and the Liver
A guide to drug handling in liver dysfunction


£33.24
RRP: £34.99 You save £1.75 (5.0%)





ISBN: 9780853697107
Publisher: Pharmaceutical Press
Date Published: Jan 2008
Format: Paperback

Drugs and the Liver is designed to assist practitioners in making pragmatic choices for their patients.

Liver disease is a widespread and increasing problem throughout the world, however little is published on how different types and degrees of liver dysfunction affect the body's ability to handle medicines.

This book aims:
•to enable the practitioner to assess liver function using biochemical markers, other tests, signs, symptoms and disease knowledge
•to identify which pharmacokinetic and pharmacodynamic parameters of a drug are likely to be affected by different types of liver disease
•to consider the impact of a drug's side effects on a patient with liver disease.

This practical guide covers background information on liver function, the principles of drug use in liver disease and includes a section of worked examples of commonly asked questions. It will be invaluable to clinical pharmacists and anyone making medicine choices in patients with liver impairment.

Contents:
Part 1 Understanding Liver Function
1. Introduction to the Anatomy of the Liver
2. Functions of the Liver
3. Causes of Liver Disease and Dysfunction
4. Assessing Liver Function

Part 2 Principles of Drug Use in Liver Disease
5. Pharmacokinetics of Drugs in Liver Disease
6. Undesirable Side Effects

Part 3 Putting the Theory Into Practice
7. Applying the Principles-introduction
8. Introducing the Aide Memoire
9. Scenario 1 Choice of Analgesia
10. Scenario 2 Choice of Anti-emetic
11. Scenario 3 Choice of Anti-hyperlipidaemic Agent
12. Scenario 4 Choice of Hormone Relacement Therapy (HRT)
13. Scenario 5 Choice of Contraceptive
Appendix 1 Detailed Description of the Patient Cases
Appendix 2 The Blank Aide Memoire Form


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